Investigator Initiated Research (IIR)

EVICR.net is a platform for multinational clinical research in Ophthalmology in Europe and a structure to support multinational Investigator-Initiated Research (IIR). IIR are studies instigated by academic researchers.

If you are an Investigator and you have an idea for a multinational clinical study, EVICR.net helps you to develop your idea in a clinical research study in ophthalmology.

Consult the EVICR.net Investigator Initiated Research (IIR) leaflet for further information.


Ongoing Investigator Initiated Research

1. PROTOCOLO AR– Observational, Longitudinal Natural History Study of Retinal Function in Eyes of Patients with Diabetes.

Sponsor: Jaeb Center for Health Research (JCHR).

Coordinating Structure: DRCR Retina Network, USA

Funding: Mary Tyler Moore Foundation

Participating Centres (7): Italy, Portugal, Spain and UK.

 

2. ClinicalTrials.gov nº NCT06709339

MONDEGO – A phase IV, multicentre, open-label, single-arm study to investigate the efficacy, safety and durability of faricimab (RO6867461) in caucasian patients with polypoidal choroidal vasculopathy”

Coordinating Investigator: Rufino Silva, Coimbra, Portugal (CS82)

Participating Centres (30): Italy, Portugal, Spain and UK.

Sponsor: AIBILI, as EVICR.net Coordinating Centre

Financial Support: Roche

 

3. ClinicalTrials.gov nº NCT05698316

INTERCEPT-AMD – A collaborative resource of Heidelberg multimodal imaging of Intermediate AMD with and without early atrophy to study prediction of disease progression

Coordinating Investigator: Sobha Sivaprasad, London, UK (CS10)

Participating Centres (20): Denmark, France, Germany, Italy, Netherlands, Portugal, Spain, Switzerland, United Kingdom

Sponsor: AIBILI, as EVICR.net Coordinating Centre

Financial Support: Boehringer Ingelheim International GmbH

 

4. ClinicalTrials.gov ID: NCT04636307

CHART – Characterization of Retinal Disease Progression in Eyes With NPDR in Diabetes Type 2 Using Non-invasive Procedures

Coordinating Investigator: J. Cunha-Vaz (CS 1)

Characterisation of Biomarkers of Diabetic Retinal Disease Progression in eyes with NPDR using non-invasive procedures.

Participating Centres (5): Portugal, Italy,  France

IIR Grant: Bayer

 

5. ClinicalTrials.gov nº NCT04281186

RECOGNISED –Retinal and Cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia

Coordinating Investigator: R. Simó, Barcelona, Spain (CS74)

Participating Centres (10): Denmark, Italy, Netherlands, Portugal, Spain and UK

Sponsor: Fundació Hospital Universitari Vall D’Hebron, VHIR, represented by Prof. Rafael Simó.

Financial Support:  Horizon 2020 – Project nº 847749

 

6. ClinicalTrials.gov nº NCT03349801

MACUSTAR – Intermediate AMD: Development of novel clinical endpoints for clinical trials in patients with a regulatory and patient access intention

Coordinating Investigator: Frank Holz, Bonn, Germany (CS15)

Participating Centres (20): Denmark, France, Germany, Italy, Netherlands, Portugal, United Kingdom

Sponsor: University Hospital Bonn

Financial Support: IMI2 and EFPIA – Project nº 116076

Positioning at the Ophthalmology Research in Europe

EVICR.net serves as a fundamental resource for the development of translational research and particularly Pharmaceutical and Medical Devices Innovation in the European Union in Ophthalmology.